Publications and Citations

As part of our funding agreement with the NIH, the MGH Vector Core is required to keep records of PIs who publish papers using our viruses. As explained in our Terms and Conditions, Users who submit a Service Request consent to

  1. Inform the MVC when one of our viruses appears in their work, and
  2. Acknowledge the MVC in their paper using the following statement:

“The ____ virus(es) was(/were) packaged at the MGH Vector Core Facility, Massachusetts General Hospital Neuroscience Center, Charlestown, MA.”

Below is a partial list of papers that have utilized viruses produced at the MGH Vector Core:

2014
Choi et al. “A three-dimensional human neural cell culture model of Alzheimer’s disease.” Nature. 514
Lai et al. “Dynamic biodistribution of extracellular vesicles in vivo using a multimodal imaging reporter.” ACS Nano. 8: 483-494.
Lai et al. “Noninvasive in vivo monitoring of extracellular vesicles.” Methods in Molecular Biology. 1098: 249-258.
2013
Badr et al. “Targeting cancer cells with the natural compound obtusaquinone.” Journal of the National Cancer Institute. 105: 643-653.
Maguire et al. “Mouse gender influences brain transduction by intravascularly administered AAV9.” Molecular Therapy. 21: 1470-1471.
Maguire et al. “Triple bioluminescence imaging for in vivo monitoring of cellular processes.” Molecular Therapy Nucleic Acids. 18: e99.
Prabhakar et al. “Regression of Schwannomas Induced by Adeno-Associated Virus-Mediated Delivery of Caspase-1.” Human Gene Therapy. 24: 152-16.
Prabhakar et al. “Stochastic model of tsc1 lesions in mouse brain.” PLoS One. 16: e64225.
Sasche et al. “BACE1 and presenilin/gamma-secretase regulate proteolytic processing of KCNE1 and 2, auxiliary subunits of voltage-gated potassium channels.” The FASEB Journal. 27: 2458-2467.
Sukhotinsky et al. “Optogenetic delay of status epilepticus onset in an in vivo rodent epilepsy model.” PLoS One. 24: e62013.
Tantama et al. “Imaging energy status in live cells with a fluorescent biosensor of the intracellular ATP-to-ADP ratio.” Nature Communications. 10: 1038.
2012
Degeling et al. “Sensitive Assay for Mycoplasma Detection in Mammalian Cell Culture.” Analytical Chemistry. 84: 4227-4232.
Maguire et al. “Microvesicle-associated AAV Vector as a Novel Gene Delivery System.” Molecular Therapy. 20: 960-971.
Niers et al. “Single reporter for targeted multimodal in vivo imaging.” Journal of the American Chemical Society. 134: 5149-5146.
2011
Badr et al. “Functional drug screening assay reveals potential glioma therapeutics.” Assay and Drug Development Technologies. 9: 281-289.
Badr et al. “Lanatoside C sensitizes glioblastoma cells to tumor necrosis factor-related apoptosis-inducing ligand and induces an alternative cell death pathway.” Neuro-Oncology. 13: 1213-1224.
Badr et al. “Suicidal gene therapy in an NF-kappaB-controlled tumor environment as monitored by a secreted blood reporter.” Gene Therapy. 18: 445-451.
Deliolanis et al. “In vivo tomographic imaging of red-shifted fluorescent proteins.” Biomedical Optics Express. 2: 887–900.
Gabriely et al. “Human glioma growth is controlled by microRNA-10b.” Cancer Research. 71: 3563-3572.
Nery et al. “TorsinA participates in endoplasmic reticulum-associated degradation.” Nature Communications. 12: 1383.
Niers et al. “Enhanced in vivo imaging of metabolically biotinylated cell surface reporters.” Analytical Chemistry. 83: 994-999.
Ma et al. “Accelerating axonal growth promotes motor recovery after peripheral nerve injury in mice.” Journal of Clinical Investigation. 121: 4332-4347.
Pike et al. “Imaging gene delivery in a mouse model of congenital neuronal ceroid lipofuscinosis.” Gene Therapy. 18: 1173–1178.
Saydam et al. “A novel imaging-compatible sciatic nerve schwannoma model.” Journal of Neuroscience Methods. 30: 75-77.
Saydam et al. “miRNA-7 attenuation in Schwannoma tumors stimulates growth by upregulating three oncogenic signaling pathways.” Cancer Research. 71: 852-861.
Smits et al. “Down-Regulation of miR-101 in Endothelial Cells Promotes Blood Vessel Formation through Reduced Repression of EZH2.” PLoS One. 28: e16282.
Tantama et al. “Imaging intracellular pH in live cells with a genetically encoded red fluorescent protein sensor.” Journal of the American Chemical Society. 133: 10034-10037.
Umera et al. “Reciprocal relationship between APP positioning relative to the membrane and PS1 conformation.” Molecular Neurodegeneration. 6: 15.
2010
Giove et al. “Transduction of the inner mouse retina using AAVrh8 and AAVrh10 via intravitreal injection.” Experimental Eye Research. 91: 652-659.
Grandi et al. “Targeting HSV-1 virions for specific binding to epidermal growth factor receptor-vIII-bearing tumor cells.” Cancer Gene Therapy. 17: 655-663.
Prabhakar et al. “Imaging and therapy of experimental schwannomas using HSV amplicon vector-encoding apoptotic protein under Schwann cell promoter.” Cancer Gene Therapy. 17: 266-274.
Uemura et al. “Substrate docking to gamma-secretase allows access of gamma-secretase modulators to an allosteric site.” Nature Communications. 12: 330-348.
2009
Badr et al. “Real-time monitoring of nuclear factor kappaB activity in cultured cells and in animal models.” Molecular Imaging. 8: 278-290.
Berg et al. “A genetically encoded fluorescent reporter of ATP:ADP ratio.” Nature Methods. 6: 161-166
Saydam et al. “Downregulated microRNA-200a in meningiomas promotes tumor growth by reducing E-cadherin and activating the Wnt/beta-catenin signaling pathway.” Molecular Cell Biology. 29: 5923-5940.
Tannous et al. “Mutant sodium channel for tumor therapy.” Molecular Therapy. 17: 810-819.
Uemura et al. “Allosteric modulation of PS1/gamma-secretase conformation correlates with amyloid beta(42/40) ratio.” PLoS One. 18: e7893
2008
Hewett et al. “siRNA knock-down of mutant torsinA restores processing through secretory pathway in DYT1 dystonia cells” Human Molecular Genetics. 17: 1436-1445.
Maguire et al. “Preventing growth of brain tumors by creating a zone of resistance.” Molecular Therapy. 16: 1695-1702.
Revised on 2014-10-14 19:27:58 UTC